# LIS requirements for toxicology labs

What a toxicology lab should demand from its laboratory information system, from presumptive screens and LC-MS/MS confirmations to medication reconciliation and clean billing.

## What does a toxicology lab need from an LIS?

A toxicology LIS should handle presumptive screens and definitive confirmations with drug-specific cutoffs, reflex rules, specimen validity testing, medication reconciliation, chain of custody, connections to immunoassay and LC-MS/MS instruments, and billing for presumptive and definitive testing.

## What is medication reconciliation in toxicology reporting?

Medication reconciliation compares each drug result with the medications the patient is prescribed, so the report shows whether findings are consistent or inconsistent with the prescription list.

## How are presumptive and definitive drug tests billed?

In the United States, presumptive drug testing generally uses CPT codes 80305 through 80307, while definitive testing uses HCPCS codes G0480 through G0483 for Medicare and drug-class codes for many commercial payers. Payer rules change, so labs should confirm current requirements.

Read the full guide at https://labdynamo.com/lis-for-toxicology-labs.